Publications by authors named "J M Mendel"
[Occurrence of Francicella tularensis subsp. holarctica in haematophagous arthropods in the Breclav district in 2022].
Epidemiol Mikrobiol Imunol
November 2024
Article Synopsis
- Tularemia, caused by the bacterium Francisella tularensis, poses a significant threat to human health but lacks extensive data on its distribution in blood-feeding arthropods.
- A study conducted in the Břeclav district in 2022 screened various hematophagous vectors, including ticks, mosquitoes, and blackflies, to check for the presence of this bacterium.
- The results revealed only two positive samples for F. tularensis subsp. holarctica, both from the tick species Dermacentor reticulatus, while no presence was found in mosquitoes or blackflies.
Article Synopsis
- The Cimicidae family consists of blood-feeding ectoparasites that primarily target warm-blooded animals, particularly swallow birds and their nestlings.
- Oeciacus hirundinis, a type of house martin bug, has not been known to transmit zoonotic pathogens, but its potential involvement in the spread of arboviruses in Europe is uncertain.
- In a study conducted in southern Moravia, Czech Republic, researchers detected Usutu virus (USUV) RNA in O. hirundinis, suggesting it might play a role in the virus's overwintering in Europe despite the absence of swallows during winter.
Article Synopsis
- - Recent research suggests that supermassive black holes may suppress star formation in massive galaxies by driving large outflows, but concrete evidence has been scarce, especially in the young universe where star formation happens quickly.
- - Although outflows of ionized gas are commonly observed, they don’t contain enough mass to hinder star formation, with more effective gas ejection expected in neutral and molecular phases that are only seen in more extreme conditions like starbursts and quasars.
- - New spectroscopy from the JWST reveals a massive galaxy at a redshift of 2.445 undergoing rapid star formation suppression, detecting a significant outflow of neutral gas that should effectively halt star creation, indicating that supermassive black holes can rapidly quench
Article Synopsis
- HPV-associated oropharyngeal cancer (HPV+OPSCC) is the most common HPV-related cancer in the U.S., but it currently lacks a screening method, making early detection challenging, despite the disease developing years before diagnosis.* -
- Researchers created an HPV whole genome sequencing test called HPV-DeepSeek, showing 99% sensitivity and specificity, which successfully identified 79% of HPV+OPSCC cases from plasma samples collected up to 10.8 years prior to cancer diagnosis.* -
- The study indicates that blood-based screening can detect HPV-associated cancers years before clinical diagnosis, emphasizing the promise of using circulating tumor DNA (ctDNA) for early cancer detection.*