Relationship between insulin sensitivity and circulating sex hormone-binding globulin levels in hyperandrogenic obese women.

The aim of this work was to examine the effect of an insulin infusion on SHBG levels as well as the relationship between SHBG levels and insulin sensitivity. Acute insulin infusion was used with the insulin-glucose clamp technique. The subjects were 14 consecutive well-characterized hyperandrogenic non-diabetic obese women without biological and echographic symptoms of polycystic ovary syndrome.

Metformin effects on peripheral sensitivity to insulin in non diabetic obese subjects.

Using the euglycaemic insulin-clamp technique we examined the effects of one-month metformin treatment on peripheral glucose utilization in non diabetic obese subjects. Two groups of obese subjects were studied in comparison with untreated lean women. Group 1 (n = 6) experienced weight loss (BMI: 32.

[Female obesity: testosteronemia is positively correlated with peripheral insulin resistance].

Hyperinsulinemia and hyperandrogenemia are frequent in obese women. The aim of this study is to examine the relationship between the degree of insulin resistance and plasma androgens, and the role of android obesity. We studied 16 obese (BMI = 39.

Thyroid hormone extraction by plasma exchange: a study of extraction rate.

How to obtain an optimal efficiency of plasma exchanges in the treatment of severe hyperthyroidism has not been defined. In order to evaluate how long the exchanges must be continued to be fully effective in extracting thyroid hormones, we evaluated the extraction rate by repeated plasma sampling in two hyperthyroid patients and three euthyroid subjects who underwent a total of seven exchanges. Plasma concentrations of thyroid hormones were also determined just before, just after, and 24 hours following the exchange.