Publications by authors named "J M Malheiros"

This study identified potential biomarkers for feed efficiency by blood plasma proteome analysis of a tropically adapted beef cattle breed. Two experimental groups were selected based on residual feed intake (RFI). The proteome was investigated by LC-MS/MS in a data-dependent acquisition mode.

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  • The study examined different methods of assessing feeding behavior in Nellore cattle, focusing on "feed events" versus "meals" to understand their genetic relationships and feed efficiency.
  • It analyzed multiple traits related to feeding events and meals, calculating heritabilities and correlations using sophisticated genetic models.
  • Results showed that more efficient cattle had shorter feeding times and faster eating rates, suggesting a genetic link between feeding behavior and feed efficiency traits.
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  • Feed costs are crucial in cattle production, making up about 75% of variable expenses, so optimizing feed efficiency is important.
  • The study analyzed the effects of traditional corn and alternative by-product diets on 14 traits related to feed efficiency and methane emissions in 52 Nellore bulls, finding that the alternative diet had better outcomes in weight gain and lower methane emissions.
  • Genetic analysis revealed 487, 484, and 499 differentially expressed genes in the liver, muscle, and rumen respectively, showing that specific genes and their connections relate to the improved traits observed with the alternative diet.
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Painful invasive procedures are often performed on newborns admitted to intensive care units (ICU). The acute and long-term effects caused by these stimuli can be investigated in animal models, such as newborn rats. Previous studies have shown that animals subjected to nociceptive stimuli in the neonatal period show sex-specific behavioral changes such as signs of anxiety or depression.

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The objectives of this study were twofold: (1) to identify potential differences in the ruminal and fecal metabolite profiles of Nelore bulls under different nutritional interventions; and (2) to identify metabolites associated with cattle sustainability related-traits. We used different nutritional interventions in the feedlot: conventional (Conv; n = 26), and by-product (ByPr, n = 26). Thirty-eight ruminal fluid and 27 fecal metabolites were significantly different (P < 0.

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