Publications by authors named "J M Madison McNiff"

Dermatopathology, like dermatology, has evolved in many directions; yet, both fields remain true to visual morphology-based diagnosis. Dr. Irwin Braverman is a role model for the intersection of these two visual fields.

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Article Synopsis
  • VEXAS syndrome is characterized by an abnormal immune response involving neutrophils but recent studies show that other cell types can also be present in the infiltrates.
  • The report discusses three cases of VEXAS syndrome, highlighting a total of seven biopsies, which revealed a consistent presence of histiocytoid cells with a distinctive feathery cytoplasm.
  • These histiocytoid cells may serve as an important diagnostic indicator for identifying VEXAS syndrome.
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Strenuous physical training increases total blood volume (BV) through expansion of plasma volume (PV) and red cell volume (RCV). In contrast, exogenous erythropoietin (EPO) treatment increases RCV but decreases PV, rendering BV stable or slightly decreased. This study aimed to determine the combined effects of strenuous training and EPO treatment on BV and markers of systemic and muscle iron homeostasis.

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The objective of this study was to examine the effect of consuming ketone monoester plus a high dose of carbohydrate from glucose (KE + CHO) on the change in erythropoietin (EPO) concentrations during load carriage exercise compared with carbohydrate (CHO) alone. Using a randomized, crossover design, 12 males consumed KE + CHO (573 mg KE/kg body mass, 110 g glucose) or CHO (110 g glucose) 30 min before 4 miles of self-paced treadmill exercise (KE + CHO:51 ± 13%, CHO: 52 ± 12% V̇O) wearing a weighted vest (30% body mass; 25 ± 3 kg). Blood samples for analysis were obtained under resting fasted conditions before (Baseline) consuming the KE + CHO or CHO supplement and immediately after exercise (Post).

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