Trimethylamine Oxidation into the Proatherogenic Trimethylamine N-Oxide Is Higher in Coronary Heart Disease Men: From the CORDIOPREV Study.

Purpose: Cardiovascular disease (CVD) is more prevalent in men than women, but the mechanisms responsible for this are not fully understood. We aimed to evaluate differences in trimethylamine (TMA), a microbial metabolite and its oxidized form, trimethylamine N-oxide (TMAO), which is thought to promote atherosclerosis, between men and women with coronary heart disease (CHD), using as a reference a non-CVD population.

Materials And Methods: This study was carried out within the framework of the CORDIOPREV study (NCT00924937; June 19, 2009), a clinical trial which included 827 men and 175 women with CHD, with a non-CVD population of 375 individuals (270 men and 105 women) as a reference group.

[Impact of the Mediterranean diet and the consumption of fermented beverages on subjective well-being in different contexts in Spain].

The relationship between the Mediterranean diet, the consumption of fermented beverages (beer and wine), and subjective well-being in Spain was investigated. Using a cross-sectional study with 2,752 participants, dietary patterns and emotional well-being were evaluated in contexts such as work, the gym, and bars/restaurants. The results showed that context significantly impacts dietary habits and well-being.

Validation of an Instrument for Detecting Problematic Internet Use in Adolescents.

Problematic internet use (PIU) has drawn attention due to its potentially negative consequences on individuals' social and personal lives. At present, a consensus on diagnostic criteria for problematic internet use remains elusive, leaving uncertainty regarding its classification as a distinct mental disorder. Extensive research efforts are underway to investigate its underlying causes, risk factors, and correlated adverse consequences.

Sex-specific differences in intestinal microbiota associated with cardiovascular diseases.

Background: Cardiovascular diseases (CVD), including coronary heart disease (CHD), display a higher prevalence in men than women. This study aims to evaluate the variations in the intestinal microbiota between men and women afflicted with CHD and delineate these against a non-CVD control group for each sex.

Methods: Our research was conducted in the framework of the CORDIOPREV study, a clinical trial which involved 837 men and 165 women with CHD.

Impact of climate change on snowpack dynamics in coastal Central-Western Greenland.

Snow patterns in ice-free areas of Greenland play important roles in ecosystems. Within a changing climate, a comprehensive understanding of the snow responses to climate change is of interest to anticipate forthcoming dynamics in these areas. In this study, we analyze the future snowpack evolution of a polar maritime Arctic location, Qeqertarsuaq (Disko Island, Central-Western Greenland).