Publications by authors named "J M Lockhart"
Article Synopsis
- The chromosome-19 miRNA cluster (C19MC) plays a role in how certain viruses affect multinucleated cells in the placenta, but its connection to multinucleation was previously unclear.
- Researchers found that C19MC is linked to meiosis-related genes and discovered a new process called meiosis-III, where nuclear division and cell division happen together to create multinucleated cells.
- The study shows that C19MC is crucial for a structure called nucle(ol)ar invasive cytoplasm (NiC) which helps in the division of nuclei and supports the creation of multinucleated cells, providing insights for cancer research, virus interactions, and potential therapies.
: The prognosis of colorectal cancer (CRC) is mainly based on the clinical stage; however, CRC is considered a complex disease due to its molecular heterogeneity. The development of novel biomarkers to improve patients' diagnosis and prognosis remains fundamental. : A cohort of forty-nine CRC patients from the National Cancer Institute of Mexico was included to collect clinical and miRNA expression data.
View Article and Find Full Text PDFEnhanced weathering and carbon dioxide (CO) mineralization of ultramafic mine wastes, including kimberlite residues from diamond mining, provides secure storage of this greenhouse gas and may physically stabilize mine impoundments. Yet, the outcomes of these processes over extensive periods (i.e.
View Article and Find Full Text PDF