Publications by authors named "J M Le Borgne"
Article Synopsis
- A study was conducted to investigate the X-chromosome's role in Alzheimer's Disease (AD), which had been overlooked in previous genome-wide association studies.
- The research included 115,841 AD cases and 613,671 controls, considering different X-chromosome inactivation (XCI) states in females.
- While no strong genetic risk factors for AD were found on the X-chromosome, seven significant loci were identified, suggesting areas for future research.
Article Synopsis
- - This study highlighted the absence of guidelines for ketamine use in chronic pain in Europe, prompting a Delphi survey among experts to create a national consensus.
- - The survey involved 28 specialists and found that 81.3% of the items achieved consensus, emphasizing ketamine's effectiveness primarily for neuropathic pain and a preferred administration method via intravenous infusion.
- - The final conclusions support quarterly ketamine treatments in a hospital setting, a one-month effectiveness evaluation, and the recommendation to combine ketamine use with non-drug therapies.
Aim: The surgical assumption of responsibility of the pancreatic pain requires either a truncular coelioscopic or radicular neurectomy of greater splanchnic nerves (gsn). The goal of our work is to describe the way and relations of the right gsn which are variable and rarely described. This constitutes an undeniable peroperational hemorrhagic risk during splanchnicectomy.
View Article and Find Full Text PDFPurpose: Recently, progress has been made in the surgical management of benign pancreatic tumors sparing as much of the pancreatic parenchyma and pancreatic function as possible. However, the main complication of partial pancreatectomy is the disruption of pancreatic ducts ensuing leak of pancreatic secretion leading to the formation of pancreatic fistulae. In this study, we attempt to precisely define the anatomy of the branch duct draining the uncinate process which is of interest to the surgeons.
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