Publications by authors named "J M Lailla Vicens"

Introduction: This narrative review aims to identify the social determinants that prevent people living with HIV from accessing specialized cancer centers and to explore factors that prevent the referral of these patients to specialized centers for HIV/cancer care in the United States and compare to patient experiences in other countries.

Methods: The review includes randomized controlled trials, cohort studies, case-control studies, qualitative studies, case series, and non-peer reviewed articles. The risk of bias was assessed using standardized tools, and data were synthesized narratively due to the heterogeneity of study designs and outcomes.

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Article Synopsis
  • Extracellular vesicles (EVs), particularly exosomes (xEVs), have been linked to the progression of Diffuse Large B-cell Lymphoma (DLBCL) and contain important biomolecules such as proteins and nucleic acids.
  • In the context of HIV, the expression of these xEVs has been associated with disease progression, highlighting their potential clinical relevance.
  • Research indicates that the biomolecules in xEVs can aid in detecting disease progression and may help in predicting treatment outcomes for DLBCL, particularly in HIV-infected patients.
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Health registries are organized systems that collect data on individuals with a particular disease, condition or exposure. The aim of this narrative review was to provide an integrated perspective from the Research Department at the Hospital Italiano de Buenos Aires, Argentina, on how health registries can be used as a bridge between healthcare, research, education, innovation and development while addressing ethical challenges. The review includes a description of the experience of a registry implemented at our institution, which has provided healthcare for 170 years, and is committed to support, education and research.

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Hepatocellular carcinoma is the most common primary liver tumor, with 905 677 diagnosed cases and 830 180 deaths, in 2020 worldwide. In Argentina, it accounts for the 9th cause of death for cancer in men and the 10th in women. Unlike other highly-prevalent tumors, scientific evidence for most therapeutic options is limited mainly to small cohorts and retrospective studies.

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