Publications by authors named "J M Kalra"

The development of new technologies in implant dentistry has led to the introduction of piezosurgery, which utilizes ultrasonic vibrations for micrometric and selective bone cutting. It is hypothesized to reduce trauma to bone tissue, thereby potentially improving the healing process compared to traditional drilling methods. This systematic review examines the differences in heat generation and pain perception between piezosurgery and conventional drilling techniques for dental implant placement.

View Article and Find Full Text PDF
Article Synopsis
  • The overuse of antibiotics has led to the emergence of antibiotic-resistant bacteria, complicating infection treatment.
  • The impact of antibiotic resistance includes longer hospital stays, increased healthcare costs, and challenges in performing surgeries that require infection prevention.
  • To combat this issue, it's essential for healthcare professionals and the public to understand the risks, and for the government to provide support to encourage the development of new antibiotics.
View Article and Find Full Text PDF

Statement Of Problem: How osseodensification osteotomy affects the implant stability and crestal bone level in patients requiring implant placement in low-density bone compared with conventional osteotomy is unclear.

Purpose: This systematic review and meta-analysis analyzed how implant stability and crestal bone level vary in a low-density bone in osseodensification osteotomy and conventional osteotomy.

Material And Methods: The SCOPUS, PUBMED, and Google Scholar databases were searched, along with a manual search, for articles published between January 2013 and January 2024.

View Article and Find Full Text PDF

Background: The tumor microenvironment is profoundly heterogeneous particularly when comparing sites of metastases. Establishing the extent of this heterogeneity may provide guidance on how best to design lipid-based drug delivery systems to treat metastatic disease. Building on our previous research, the current study employs a murine model of metastatic cancer to explore the distribution of ~ 100 nm liposomes.

View Article and Find Full Text PDF

Phosphorylation of smooth muscle (SM) myosin regulatory light chain (RLC) is a critical switch leading to SM contraction. The canonical view held that only the short isoform of myosin light chain kinase (MLCK1) catalyzed this reaction. It is now accepted that auxiliary kinases may contribute to vascular SM tone and contractility.

View Article and Find Full Text PDF