Publications by authors named "J M Inadomi"
Article Synopsis
- Blood-based biomarker tests could potentially transform colorectal cancer screening, but their effectiveness and cost-effectiveness compared to fecal testing and colonoscopy depend on specific sensitivities, costs, and testing intervals.
- A study using modeling techniques found that annual fecal immunochemical testing and colonoscopy provide more quality-adjusted life-years (QALY) at a lower cost than a blood test that meets minimum CMS standards.
- For blood tests to be recommended, they must achieve a higher sensitivity for advanced adenomas and be priced below $125; otherwise, they are less beneficial than current screening methods.
Background & Aims: Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC). Endoscopic eradication therapy (EET) can be effective in eradicating BE and related neoplasia and has greater risk of harms and resource use than surveillance endoscopy. This clinical practice guideline aims to inform clinicians and patients by providing evidence-based practice recommendations for the use of EET in BE and related neoplasia.
View Article and Find Full Text PDFBackground: Social determinants of health (SDoH) have been associated with disparate outcomes among those with metabolic dysfunction-associated steatotic liver disease (MASLD) and its risk factors. To address SDoH among this population, real-time SDoH screening in clinical settings is required, yet optimal screening methods are unclear. We performed a scoping review to describe the current literature on SDoH screening conducted in the clinical setting among individuals with MASLD and MASLD risk factors.
View Article and Find Full Text PDFBackground & Aims: A blood-based colorectal cancer (CRC) screening test may increase screening participation. However, blood tests may be less effective than current guideline-endorsed options. The Centers for Medicare & Medicaid Services (CMS) covers blood tests with sensitivity of at least 74% for detection of CRC and specificity of at least 90%.
View Article and Find Full Text PDF