Publications by authors named "J M Hermann"

Objectives: In the current clinical practice of thermal ablation treatment for liver tumors, achieving consistent and effective clinical outcomes across tumors of varying shapes, sizes and locations remains challenging. The aim of this study was to evaluate the repeatability of a novel robotic approach for configurable ablation of distinct tumor shapes and compare it to the standard ablation technique for creating ellipsoidal ablation volumes.

Materials And Methods: The repeatability was evaluated in terms of width variability in created ablation volumes.

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Quantum sensors using solid-state spin defects excel in the detection of radiofrequency (RF) fields, serving various applications in communication, ranging, and sensing. For this purpose, pulsed dynamical decoupling (PDD) protocols are typically applied, which enhance sensitivity to RF signals. However, these methods are limited to frequencies of a few megahertz, which poses a challenge for sensing higher frequencies.

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Background: Evidence regarding the effect of long-term exposure to particulate matter (PM) 2.5 and comorbid cancer and cardiovascular disease (CVD) mortality is limited.

Objectives: In this study, the author report the association between long-term exposure to PM 2.

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Article Synopsis
  • Angiotensin II (Ang II) is crucial for blood pressure regulation, and a modified version called pyruvamide-Ang II (Ang P), created with a cheaper vitamin B derivative (pyridoxal-5'-phosphate), may provide a cost-effective treatment for hypertension.
  • Studies showed that Ang P leads to lower calcium entry in vascular smooth muscle cells and has a weaker binding affinity to the angiotensin II type 1 receptor, resulting in less vasoconstriction compared to traditional Ang II.
  • In tests on rats, using PLP significantly reduced blood pressure in spontaneously hypertensive rats and prevented blood pressure spikes in normal rats when treated with both Ang II and PLP, suggesting
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  • * Research in mice shows that the absence of certain TRPC channel proteins (specifically TRPC5) leads to a significant reduction in adrenaline release during insulin-induced hypoglycemia.
  • * There is a newly identified signaling pathway where specific receptor activation leads to TRPC5 channel stimulation, impacting adrenaline secretion, with similar plasma metabolite changes noted in both TRPC5-deficient mice and HAAF patients.
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