Publications by authors named "J M Gonzalez-Clemente"

Objective: To provide practical recommendations for the comprehensive approach of people with type 2 diabetes according to evidence-based medicine.

Participants: Members of the Diabetes Knowledge Area of the Spanish Society of Endocrinology and Nutrition.

Methods: The recommendations were formulated according to the degrees of evidence of the Standards of Medical Care in Diabetes-2022.

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Article Synopsis
  • This study investigates the link between vascular aging (specifically arterial stiffness) and inflammation in adults with type 1 diabetes (T1D) by measuring serum N-glycans GlycA and GlycB.
  • Results showed that individuals with T1D had significantly higher arterial stiffness and levels of GlycA and GlycB compared to healthy subjects, and these measurements correlated with arterial stiffness levels.
  • The findings suggest that assessing GlycA and GlycB could be useful for evaluating vascular aging in long-term T1D patients without prior cardiovascular issues.
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Objective: Obesity is characterized by a low-grade inflammatory state in adipose tissue. Tumor Necrosis Factor Weak Inducer of Apoptosis (TWEAK) and Cluster of Differentiation 163 (CD163) are cytokines potentially involved in the pathogenesis of obesity. Little is known about them in children.

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Dapagliflozin is a selective sodium-glucose cotransporter 2 inhibitor (SGLT2i) indicated for the treatment of type 2 diabetes mellitus (T2DM), heart failure with reduced ejection fraction and chronic kidney disease. In all indications, treatment can be initiated in adults with estimated glomerular filtration rate of at least 25 mL/min/1.73 m.

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