Publications by authors named "J M Ghere"
The list of EPA-approved disinfectants for coronavirus features many products for use on hard, non-porous materials. There are significantly fewer products registered for use on porous materials. Further, many common, high-touch surfaces fall in between non-porous materials such as glass and porous materials such as soft fabrics.
View Article and Find Full Text PDFAims: This study evaluated the residual efficacy of commercially available antimicrobial coatings or films against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on non-porous surfaces.
Methods And Results: Products were applied to stainless steel or ABS plastic coupons and dried overnight. Coupons were inoculated with SARS-CoV-2 in the presence of 5% soil load.
This study evaluated the efficacy of detergent-based surface cleaning methods against Murine Hepatitis Virus A59 (MHV) as a surrogate coronavirus for SARS-CoV-2. MHV (5% soil load in culture medium or simulated saliva) was inoculated onto four different high-touch materials [stainless steel (SS), Acrylonitrile Butadiene Styrene plastic (ABS), Formica, seat fabric (SF)]. Immediately and 2-hr post-inoculation, coupons were cleaned (damp wipe wiping) with and without pretreatment with detergent solution or 375 ppm hard water.
View Article and Find Full Text PDFArticle Synopsis
- Human cytomegalovirus (CMV) infection can cause kidney transplant issues, especially when paired with acute rejection, and this study looks at CMV-induced antibodies in that context.
- Researchers used mice to assess immunoglobulin G (IgG) and complement deposition in various types of CMV-infected kidney transplants, comparing B cell-deficient recipients and the effects of treatment with immune sera.
- Findings showed that kidney transplants with certain CMV profiles had higher IgG and complement deposition, leading to more significant tissue damage, suggesting that the body's immune response to CMV plays a role in kidney transplant rejection.