Publications by authors named "J M Frazao"

Open ventral hernia repair is one of the most commonly performed surgeries by general surgeons worldwide. In the case of complex incisional hernias, there are adjunct techniques that can help abdominal wall reconstruction surgery, such as type A botulinum toxin (BTA), whose injection results in muscle relaxation and growth of muscle fiber length, allowing fascial closure without the need for advanced techniques. We report a case of a male patient who underwent ultrasound-guided BTA injection in the abdominal wall and, five days later, was admitted to our emergency department with dysarthria, muscular weakness, dyspnea on small exertion, and constipation.

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Calcitriol and calcimimetics are used to treat hyperparathyroidism secondary to chronic kidney disease (CKD). Calcitriol administration and the subsequent increase in serum calcium concentration decrease parathyroid hormone (PTH) levels, which should reduce bone remodeling. We have previously reported that, when maintaining a given concentration of PTH, the addition of calcimimetics is associated with an increased bone cell activity.

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Intussusception occurs when a part of the intestine slides into its distal adjacent portion and is a surgical emergency. Adult colocolic intussusception is rare, but it is a severe condition and is usually associated with a presence of a tumoral process. We present the case of a frail male patient admitted to our emergency department with abdominal pain, prostration, and dyspnea.

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Article Synopsis
  • Droplet-based microfluidic technology is used to create large numbers of tiny droplets for screening molecules or cells, but current monitoring methods lack accessibility and are often expensive.
  • * An open-source programming language called Bonsai was validated to enable easy and real-time measurement of droplets in microfluidic devices, using simple imaging techniques.
  • * The developed system provides a user-friendly, cost-effective tool for researchers of all skill levels to monitor and analyze droplet parameters like size and speed in real-time without needing extensive programming knowledge.
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