Publications by authors named "J M Ferrar"
Single-molecule fluorescence resonance energy transfer (smFRET) is a powerful technique for studying the structural dynamics of protein molecules or detecting interactions between protein molecules in real time. Due to the high sensitivity in spatial and temporal resolution, smFRET can decipher sub-populations within heterogeneous native state conformations, which are generally lost in traditional measurements due to ensemble averaging. In addition, the single-molecule reconstitution allows protein molecules to be observed for an extensive period of time and can recapitulate the geometry of the cellular environment to retain biological function.
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- The study investigated how introducing draught alcohol-free beer in pubs and bars in England affected the sales of alcoholic beverages and overall revenue.
- It involved a randomized crossover trial in 14 venues, alternating between periods of selling the alcohol-free option and normal operations over eight weeks.
- Findings showed that the sale of draught alcoholic beer dropped by 4% to 5% with the introduction of alcohol-free beer, but there was no significant change in total revenue from all drinks.
Aims: To estimate the impact on selection and actual purchasing of (a) health warning labels (text-only and image-and-text) on alcoholic drinks and (b) calorie labels on alcoholic and non-alcoholic drinks.
Design: Parallel-groups randomised controlled trial.
Setting: Drinks were selected in a simulated online supermarket, before being purchased in an actual online supermarket.
Background: Increasing the availability of non-alcoholic options is a promising population-level intervention to reduce alcohol consumption, currently unassessed in naturalistic settings. This study in an online retail context aimed to estimate the impact of increasing the proportion of non-alcoholic (relative to alcoholic) drinks, on selection and purchasing of alcohol.
Methods And Results: Adults (n = 737) residing in England and Wales who regularly purchased alcohol online were recruited between March and July 2021.
Background: The positive and negative effects of interacting with web-based content on mental health, and especially self-harm, are well documented. Lived experience stories are one such type of static web-based content, frequently published on health care or third-sector organization websites, as well as social media and blogs, as a form of support for those seeking help via the web.
Objective: This study aimed to increase understanding about how people who self-harm engage with and evaluate web-based lived experience stories.