Publications by authors named "J M Dagle"

As more neonatal centers are caring for premature infants at 21-23 weeks' gestational age (GA), a growing need for improved practices related to routine skin care exists. Approach to skin care in this GA is challenging because the skin barrier is not completely formed at this developmental stage, leading to an increased risk of insensible water loss; increased sodium and nutritional requirement; and greater susceptibility to injury, infection, and temperature instability. Effective skin care in this population requires a proactive, standardized, multidisciplinary approach.

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Article Synopsis
  • * It analyzed data from two groups of infants before and after the protocol's implementation, showing significant growth improvements (body weight and head circumference) in those born at 26-29 weeks.
  • * Results indicated that the protocol reduced the need for mechanical ventilation but did not increase the risk of health issues like hypertension or infections in extremely preterm infants.
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Background: Data on clinical outcomes of infants with birthweights less than 501 g (ELBW) are limited.

Objective: To evaluate management strategies and clinical outcomes of ELBWinfants compared to infants weighing 501-750 g (ELBW).

Methods: A retrospective study of all ELBW and ELBW infants born between 2012 and 2022 at a center utilizing first intention high frequency jet ventilation was performed.

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Importance: Sudden infant death syndrome (SIDS) is a major cause of infant death in the US. Previous research suggests that inborn errors of metabolism may contribute to SIDS, yet the relationship between SIDS and biomarkers of metabolism remains unclear.

Objective: To evaluate and model the association between routinely measured newborn metabolic markers and SIDS in combination with established risk factors for SIDS.

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Background: Hemodynamically significant patent ductus arteriosus (hsPDA) shunt may predispose infants to retinopathy of prematurity (ROP) because of its higher preductal cardiac output and blood oxygen content, which may augment ocular oxygen delivery.

Methods: A retrospective cohort study of preterm infants, born at <27 weeks' gestation and admitted at <24h postnatal age to a large quaternary referral was conducted. The primary composite outcome was death at <32 weeks or moderate-to-severe ROP (≥stage 2 or requiring treatment) in either eye.

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