Publications by authors named "J M Christenson"
Background: Previous studies have reported race-based health disparities in North America. It is unknown if emergency medical service (EMS) treatment of out-of-hospital cardiac arrest (OHCA) varies based on race. We sought to compare markers of resuscitation intensity among different racial groups.
View Article and Find Full Text PDFBackground: For emergency department (ED) patients with cardiac chest pain, introduction of high-sensitivity troponin (hsTnT) pathways has been associated with reductions in length of stay of less than 1 h.
Methods: At two urban Canadian sites, we introduced hsTnT on January 26, 2016. While the prior diagnostic algorithm required troponin testing at 0 and 6 h, serial hsTnT serial testing was conducted at 0 and 3 h.
Out-of-hospital cardiac arrest (OHCA) is a global health problem affecting approximately 4.4 million individuals yearly. OHCA has a poor survival rate, specifically when unwitnessed (accounting for up to 75% of cases).
View Article and Find Full Text PDFArticle Synopsis
- TDO2 is expressed at higher levels than IDO1 in triple-negative breast cancer (TNBC).
- Knocking down TDO2 can trigger an increase in IDO1 as a compensatory response.
- A new dual inhibitor targeting both TDO2 and IDO1 reduces tryptophan catabolism, inhibits anchorage-independent survival, and decreases invasive capabilities of cancer cells.
Long-term outcomes among out-of-hospital cardiac arrest survivors with reversible vs. non-reversible causes.
Eur Heart J Acute Cardiovasc Care
October 2024
Article Synopsis
- The study aimed to analyze long-term outcomes in survivors of out-of-hospital cardiac arrest (OHCA) based on the cause of the arrest, particularly focusing on reversible vs. non-reversible etiologies.
- Researchers examined data from the British Columbia Cardiac Arrest registry, categorizing patients by their OHCA cause and measuring outcomes like mortality and rehospitalization over three years.
- Results indicated that survivors with reversible ischemic causes had the best outcomes, while those with reversible non-ischemic causes experienced the worst outcomes, highlighting the importance of identifying the underlying cause of cardiac arrests.