Publications by authors named "J M Chiang"
Investigation of RNA Viruses in Latreille, 1809 (Diptera: Ceratopogonidae) in a Mining Complex in the Southeastern Region of the Brazilian Amazon.
Viruses
November 2024
The biting midges Latreille, 1809 (Diptera: Ceratopogonidae) is highly relevant to epidemiology and public health, as it includes species that are potential vectors of human and animal arboviruses. The aim of this study was to investigate the presence of RNA viruses in species of the genus collected in the Carajás mining complex in the state of Pará. The biting midges were collected in the municipalities of Canaã dos Carajás, Curionópolis and Marabá and morphologically identified.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the effects of ceftriaxone and adipose-derived mesenchymal stem cells (ADMSCs) on protecting the spinal cord from acute spinal infection (ASI) in rats.
- Results showed that the combination treatment of ceftriaxone and ADMSCs led to significantly lower inflammatory markers and bacterial counts compared to the individual treatments, indicating better inflammation control and tissue preservation.
- By day 28, the combination therapy demonstrated superior results in protecting vertebral bone and spinal cord integrity compared to each treatment alone, suggesting a potential therapeutic strategy for ASI.
The importance of extra-nodal disease has been well recognized in follicular lymphoma, and is incorporated into various prognostic tools. However, the optimal treatment strategy for this subgroup remains unclear. In this multicenter retrospective study, we analyzed 143 patients who received either R-CHOP or Bendamustine-Rituximab (BR), with a median follow-up of 69.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to compare the effectiveness of combined therapy with probiotics and cytokine-induced killer (CIK) cells against colorectal cancer (CRC) growth and metastasis in mice versus using either treatment alone.
- - Results showed that both probiotics and CIK cells significantly reduced CRC cell viability and increased apoptosis, with the combination of both therapies being the most effective at suppressing tumor growth and metastasis.
- - Mice treated with combined probiotics and CIK therapy exhibited the least amount of tumor presence and related biomarkers in the liver compared to the other treatment groups, indicating a stronger anti-cancer effect.
Article Synopsis
- * Research on Dlgap2 mutant mice showed that while their overall odor detection was similar to normal mice, they showed less interest in certain smells (banana and almond) but reacted more to unfamiliar bedding smells.
- * The absence of DLGAP2 protein in Homo mutant mice affected their brain's response to odors, which suggests altered synaptic signaling in their olfactory systems and could inform future strategies for diagnosing and treating ASD-related olfactory issues.