Risk factors for early-onset basal cell carcinomas and the trend towards their female predominance.

Background: A dramatic rise in the incidence rates of basal cell carcinoma (BCC) in young women has been reported.

Objectives: We investigate potential risk factors (RF) for sporadic BCC in young patients and the current distribution of such RF in the general population of Catalonia, comparing the differences among men and women.

Patients And Methods: A case-control study was performed, 69 BCCs diagnosed in patients ≤ 45 years of age vs.

Interplay between Humoral and CLA T Cell Response against in Psoriasis.

(CA) infections have been associated with psoriasis onset or disease flares. However, the integrated immune response against this fungus is still poorly characterized in psoriasis. We studied specific immunoglobulins in plasma and the CA response in cocultures of circulating memory CD45RA cutaneous lymphocyte antigen (CLA) T cell with autologous epidermal cells from plaque and guttate psoriasis patients (cohort 1, = 52), and also healthy individuals ( = 17).

Epidemiology of Psoriasis. A Population-Based Study.

Background And Objectives: Psoriasis is a chronic immunoinflammatory skin disease very frequent in the western world. Several authors have tried to calculate its prevalence in different regions, although most of them obtained the data from surveys and there are few publications from Mediterranean areas. The objective of our study was to analyze the prevalence and severity of psoriasis in Lleida (a northeastern region in Spain), identify age and sex specific differences and compare our results with other European series.