[VY-plasty for chronic quadriceps tendon rupture].

Objective: Lengthening of the quadriceps tendon for dehiscence in chronic rupture.

Indications: Chronic rupture of the quadriceps tendon with delayed diagnosis or failure of primary refixation with a dehiscence between 1 and 5 cm.

Contraindications: Dehiscence of more than 5 cm.

[Reconstruction of the medial collateral ligament complex with a flat semitendinosus auto- or allograft].

Objective: Replacement of superficial medial collateral ligament (sMCL) and posterior oblique ligament (POL) with an allograft.

Indications: Chronic 3° isolated medial instability and combined anteromedial or posteromedial instability.

Contraindications: Infection, open growth plates, restricted range of motion (less than E/F 0-0-90°).

[Medial closing wedge osteotomy for correction of valgus deformity].

Objective: Correction of a proximal tibial valgus deformity.

Indications: Lateral osteoarthritis of the knee or cartilage damage in a valgus deformity > 5° with a medial proximal tibial angle (MPTA) > 90°.

Contraindications: Medial proximal tibial angle < 90°, medial cartilage damage, medial meniscus loss.

Characterization of Organic Anion and Cation Transport in Three Human Renal Proximal Tubular Epithelial Models.

The polarised expression of specific transporters in proximal tubular epithelial cells is important for the renal clearance of many endogenous and exogenous compounds. Thus, ideally, the in vitro tools utilised for predictions would have a similar expression of apical and basolateral xenobiotic transporters as in vivo. Here, we assessed the functionality of organic cation and anion transporters in proximal tubular-like cells (PTL) differentiated from human induced pluripotent stem cells (iPSC), primary human proximal tubular epithelial cells (PTEC), and telomerase-immortalised human renal proximal tubular epithelial cells (RPTEC/TERT1).

Reconstruction of the Medial Collateral Ligament Complex With a Flat Allograft Semitendinosus Tendon.

The aim of this Technical Note is to reconstruct the medial collateral ligament complex with the superior medial collateral ligament and posterior oblique ligament as anatomically as possible. An allograft or contralateral semitendinosus autograft is used for anatomic reconstruction of the superior medial collateral ligament and posterior oblique ligament. After bony fixation, the tendon bundles are sutured to the remnants of the medial collateral ligament complex.