Publications by authors named "J M Buesa"
Article Synopsis
- The study investigates the effects of threatened preterm labor (TPL) on children's development, focusing on children at 2 years old born to mothers diagnosed with TPL.
- It categorizes participants into three groups based on gestational age at delivery: Full-term, Late Preterm, and Very Preterm TPL, alongside a control group of full-term mothers and infants without TPL.
- Results indicate that TPL children, regardless of gestational age, showed poorer emotional regulation and increased inhibition issues, with Very Preterm TPL children facing even more significant challenges in psychomotor skills and executive functions.
Rotavirus remains a significant public health threat, especially in low-income countries, where it is the leading cause of severe acute childhood gastroenteritis, contributing to over 128,500 deaths annually. Although the introduction of the Rotarix and RotaTeq vaccines in 2006 marked a milestone in reducing mortality rates, approximately 83,158 preventable deaths persisted, showing ongoing challenges in vaccine accessibility and effectiveness. To address these issues, a novel subcutaneous vaccine formulation targeting multiple rotavirus genotypes has been developed.
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- Fecal-orally transmitted gastroenteritis viruses, especially human noroviruses, are a major public health issue linked to contaminated water, but their infectivity has been hard to measure in lab settings.
- This study tested the human intestinal enteroids (HIE) model to evaluate the infectivity of various gastroenteritis viruses in wastewater, finding that this method efficiently supported viral replication without needing complex sample handling.
- Of the 28 wastewater samples tested, 57% showed viral replication, with multiple viral types coexisting in some samples, demonstrating the HIE model's effectiveness in identifying infectious gastroenteritis viruses in real-world wastewater.
Background: Recent research suggests that children born after suspected preterm labor may observe a potential cluster with different attention deficit hyperactivity disorder features, depending on the time of birth. However, the evolution of symptoms and their predictors remain unknown in this population.
Objective: This study aimed to examine the trajectories of attention deficit hyperactivity disorder symptoms of children born after suspected preterm labor, between ages 2 and 6 years, considering prematurity condition and comparing with controls.
Rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in children under 5 years old worldwide, and several studies have demonstrated that histo-blood group antigens (HBGAs) play a role in its infection process. In the present study, human stool filtrates from patients diagnosed with RV diarrhea (genotyped as P[8]) were used to infect differentiated Caco-2 cells (dCaco-2) to determine whether such viral strains of clinical origin had the ability to replicate in cell cultures displaying HBGAs. The cell culture-adapted human RV Wa model strain (P[8] genotype) was used as a control.
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