Publications by authors named "J M Brisset"
Article Synopsis
- * The majority of the patients had severe COVID-19, with 90% showing abnormal ASL perfusion, particularly hypoperfusion in the temporal poles and frontal lobes, even if traditional MRI scans appeared normal.
- * The findings highlight that over 80% of these patients exhibited significant brain perfusion deficits, suggesting that neurological complications in COVID-19 can occur independently of visible lesions on standard MRI scans.
Objectives: To determine whether diffusion-weighted imaging (DWI) can help to distinguish early stage autoimmune (AI) and herpes simplex virus (HSV) encephalitides.
Methods: This case-control study included patients from a multi-center cohort of AI encephalitides whose initial MRI including DWI was performed within ten days after symptoms onset. They were compared with patients with HSV encephalitis enrolled prospectively in a single-center from June, 2020 to December, 2020.
Proton magnetic resonance spectroscopy (H-MRS) provides a non-invasive biochemical profile of brain tumors. The conventional H-MRS methods present a few challenges mainly related to limited spatial coverage and low spatial and spectral resolutions. In the recent past, the advent and development of more sophisticated metabolic imaging and spectroscopic sequences have revolutionized the field of neuro-oncologic metabolomics.
View Article and Find Full Text PDFBackground: While malaria morbidity and mortality have declined since 2000, viral central nervous system infections appear to be an important, underestimated cause of coma in malaria-endemic Eastern Africa. We aimed to describe the etiology of non-traumatic comas in young children in Benin, as well as their management and early outcomes, and to identify factors associated with death.
Methods: From March to November 2018, we enrolled all HIV-negative children aged between 2 and 6 years, with a Blantyre Coma Score ≤ 2, in this prospective observational study.