Publications by authors named "J M Bremner"
Environmental hazards associated with the global food system threaten societal integrity. Yet, there is a major data gap in the global understanding of how the prevalence of hazards is changing over time, how different classes of hazard are distributed, and whether the combined literature represents hazard prevalence equitably across research, policy and legislation, and news. Here, we explore this data gap, leveraging global research, policy, and news databases.
View Article and Find Full Text PDFAims: The mechanisms linking acute psychological stress to cardiovascular disease (CVD) mortality are incompletely understood. We studied the relationship of electrocardiographic measures of autonomic dysfunction during acute mental stress provocation and CVD death.
Methods And Results: In a pooled cohort of 765 participants with stable CVD from two related studies, we collected Holter data during standardized laboratory-based mental stress testing with a speech task and followed them for events.
Article Synopsis
- PTSD is linked to a higher risk of heart failure hospitalizations in individuals with coronary artery disease, with those diagnosed having a 4.4 times greater risk of hospitalizations compared to those without PTSD.
- The study involved 736 participants, revealing that 9.4% had PTSD, and higher PTSD symptom scores correlated with increased heart failure events.
- While PTSD is strongly associated with heart failure, it does not appear to influence rates of cardiovascular death or nonfatal heart attacks unrelated to heart failure hospitalizations.
Article Synopsis
- COVID infection can lead to Long COVID, which causes various long-term neurological and mental health issues, but the exact causes and range of symptoms are still unclear.
- A literature review from multiple databases highlights that many patients experience symptoms like loss of smell and increased fatigue, alongside significant anxiety and mood disorders.
- Neuropsychological and brain imaging studies indicate a link between the severity of symptoms and cognitive dysfunction, as well as observable changes in brain structure in Long COVID patients, calling for further research to understand the underlying mechanisms.
Excessive peripheral microvascular constriction during acute psychological stress reflects similar changes in coronary blood flow and is a predictor of adverse cardiovascular outcomes. Among individuals with coronary artery disease (CAD), we sought to determine if genetic factors contribute to the degree of microvascular constriction during mental stress. A total of 580 stable CAD individuals from two prospective cohort studies underwent mental stress testing.
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