Publications by authors named "J M Boeira"
A Framework for Automatic Recognition of Cell Damage on Microscopic Images using Artificial Neural Networks.
Annu Int Conf IEEE Eng Med Biol Soc
July 2018
Despite several technological advances in the past years, the vast majority of microscopy examinations continue to be performed in a very laborious, time-consuming manner, requiring highly experienced personnel to spend several hours to visually examine each microscope slide. Due to recent improvements in modern Digital Image Processing, professionals that work on microscopic exams could benefit from new tools that can apply image processing possibilities to their specific field. We propose a framework consisting of an image segmentation stage, feature extraction, and then a Shallow Neural Network related to human perception.
View Article and Find Full Text PDFUnlabelled: Passiflora alata is an official species of Brazilian Pharmacopoeia and its aerial parts are used as medicinal plant by local population as well as constitutes many phytomedicines commercialized in Brazil as sedative.
Aims Of Study: To evaluate the acute and sub-acute toxicity and genotoxicity of an aqueous spray-dried extract (PA) of Passiflora alata (2.6% flavonoids).
Article Synopsis
- The study investigated the impact of pesticide exposure on farm workers in Rio Grande do Sul, Brazil, by measuring specific enzyme activities and DNA damage.
- Results showed significant reductions in butyrylcholinesterase (BChE) and delta-aminolevulinic acid dehydratase (ALA-D) activities among exposed workers compared to a control group.
- The analysis indicated elevated DNA damage in the exposed group but found no notable differences in hematological, lipid, or micronucleus test results based on age or smoking status; the use of personal protective equipment (PPE) appeared crucial for reducing contamination risk.
The beta-carboline alkaloids found in medical plants and in a variety of foods, beverages and cigarette smoke have a range of action in various biological systems. In vitro studies have demonstrated that these alkaloids can act as scavengers of reactive oxygen species. In this paper, we report the in vivo antioxidative properties of the aromatic (harmane, harmine, harmol) and dihydro-beta-carbolines (harmaline and harmalol) studied by using Saccharomyces cerevisiae strains proficient and deficient in antioxidant defenses.
View Article and Find Full Text PDFbeta-carboline alkaloids are found in several medicinal plants and display a variety of actions on the central nervous, muscular and cardiovascular systems. The aim of the present study was to evaluate the effects of systemic administration of beta-carboline alkaloids on object recognition in mice. Adult Swiss mice received an intra-peritoneal injection (i.
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