Publications by authors named "J M Binnekade"
Background: Transfusion guidelines regarding platelet-count thresholds before the placement of a central venous catheter (CVC) offer conflicting recommendations because of a lack of good-quality evidence. The routine use of ultrasound guidance has decreased CVC-related bleeding complications.
Methods: In a multicenter, randomized, controlled, noninferiority trial, we randomly assigned patients with severe thrombocytopenia (platelet count, 10,000 to 50,000 per cubic millimeter) who were being treated on the hematology ward or in the intensive care unit to receive either one unit of prophylactic platelet transfusion or no platelet transfusion before ultrasound-guided CVC placement.
Article Synopsis
- This study looked at how burn patients in intensive care are helped with breathing machines, specifically using something called lung-protective ventilation.
- Researchers checked the breathing settings of 160 patients from 28 hospitals in 16 countries to see if using low volumes of air helped them recover better.
- They found that most patients were getting this type of ventilation, but it didn't seem to make a big difference in how many days they were off the ventilator or if they were alive 28 days later.
Article Synopsis
- A systematic review was conducted to evaluate whether venoarterial extracorporeal membrane oxygenation (VA-ECMO) improves survival rates in patients with acute pulmonary embolism (PE).
- The analysis included 29 studies with a total of 1,947 patients but found no significant difference in short-term survival between those treated with VA-ECMO and a control group (RR 0.91).
- Factors influencing survival included age over 60 years, which correlated with lower survival rates, while those who underwent surgical embolectomy had better survival outcomes (RR 1.96).
Background: Intraoperative hypotension, with varying definitions in literature, may be associated with postoperative complications. The aim of this meta-analysis was to assess the association of intraoperative hypotension with postoperative morbidity and mortality.
Methods: MEDLINE, Embase and Cochrane databases were searched for studies published between January 1990 and August 2018.