Publications by authors named "J M Bangsborg"
Background: It has been suggested that neuroborreliosis in children can manifest as psychiatric neurodevelopmental disorders or cause long-term neurodevelopmental sequelae. However, previous studies were limited by size and design.
Methods: We performed a nationwide, population-based, matched cohort study in Denmark between 1995 and 2021.
Background: Few studies have investigated the risk of psychiatric neurodevelopmental disorders (PNDD) after childhood meningitis.
Methods: Nationwide population-based cohort study (Denmark, 1995-2021) of children with positive cerebrospinal fluid for bacteria or enterovirus, stratified on age as young infants (0 to <90 days, = 637) or older children (≥90 days to <17 years, = 1,218). We constructed a comparison cohort from the general population ( = 18,550), and cohorts of siblings of participants.
Background: Early initiation of targeted antibiotic therapy is important to achieve the best patient outcomes in intubated patients with pneumonia in the intensive care unit (ICU). This study aimed to investigate the applicability of multiplex polymerase chain reaction (PCR) in an ICU by comparing the test results to the results of conventional microbiological methods to assess the possible impact on antibiotic therapy.
Method: This retrospective study investigated adult patients with pneumonia on mechanical ventilation in the ICU.
Objectives: To identify diagnostic opportunities, we investigated healthcare-seeking behaviour among patients with Lyme neuroborreliosis (LNB) within 28 weeks before diagnosis.
Methods: We conducted a population-based, nationwide matched nested case-control study (Denmark, 2009-2021). As cases, we included all Danish residents with LNB (positive Borrelia burgdorferi intrathecal antibody index test and cerebrospinal fluid pleocytosis).
Article Synopsis
- The study aimed to examine how often patients with neuroborreliosis receive additional antibiotic treatment after their initial doxycycline therapy due to lingering symptoms.
- Conducted in Denmark between 2009-2021, the research compared 463 neuroborreliosis patients with 2,315 matched individuals from the general population, focusing on doxycycline and phenoxymethylpenicillin usage.
- Results showed that neuroborreliosis patients were significantly more likely to receive doxycycline again within one year (38.6 times more) compared to the general population, while there was no difference in phenoxymethylpenicillin prescriptions, indicating a specific need for doxycycline rather than just healthcare-seeking behavior.