Number, treatment, and mortality of paediatric pelvic ring fractures in two level 1 trauma centres in the Netherlands : a multicentre retrospective cohort study.

Aims: Paediatric pelvic ring fractures are rare but severe injuries, presenting significant treatment challenges. This study aimed to analyze patient characteristics and explore trends in incidence, treatment methods, and mortality associated with these injuries.

Methods: This multicentre, retrospective cohort study analyzed paediatric patients (aged ≤ 18 years) with pelvic ring fractures treated between 2001 and 2021 at two level 1 trauma centres.

Survivin in cardiovascular diseases and its therapeutic potential.

Aberrant changes in cell behaviors, such as proliferation, apoptosis, and migration, are some of the contributing factors to the development of various cardiovascular diseases (CVDs) and pathologies, including atherosclerosis, neointimal hyperplasia, and heart failure. In recent years, numerous studies have identified survivin, a key player in the anti-apoptotic pathway, to be extensively involved in modulating cellular functioning in cancer, with many reaching clinical trials. Though seemingly different, CVDs and cancer share abundant similarities regarding abnormal cell modifications and behaviors.

A decade of sub-arcsecond imaging with the International LOFAR Telescope.

The International LOFAR Telescope (ILT) is a pan-European radio interferometer with baselines up to 2000 km. This provides sub-arcsecond resolution at frequencies of <200 MHz. Since starting science operations in 2012, the ILT has carried out observations for the state-of-the-art LOFAR Two-metre Sky Survey, which has 6 arcsec resolution at 144 MHz.

Ac-225 radiochemistry through the lens of [Ac]Ac-DOTA-TATE.

Background: Targeted alpha therapy with Ac-225 showed to be effective in treating metastatic cancers. However, the complex decay chain requires optimized radiolabeling and quality control. This study aims to determine critical parameters and establish optimal labeling and accurate measuring techniques for radiochemical yield and purity with DOTA-TATE as a model molecule.