Munchausen syndrome (MS), a complex form of factitious disorder (FD), presents significant diagnostic and management challenges in emergency and hospital settings. Patients deliberately fabricate or induce symptoms to gain medical attention, often leading to unnecessary interventions, resource misallocation, and iatrogenic harm. This study highlights the diagnostic complexity and the need for multidisciplinary management of Munchausen syndrome through a detailed case report and literature review.
View Article and Find Full Text PDFBackground/objectives: DNA vaccines are rapidly produced and adaptable to different pathogens, but they face considerable challenges regarding stability and delivery to the cellular target. Thus, effective delivery methods are essential for the success of these vaccines. Here, we evaluated the efficacy of capsules derived from the cell wall of the yeast as a delivery system for DNA vaccines.
View Article and Find Full Text PDFTropical cyclone risks are expected to increase with climate change. One such risk is extreme ocean waves generated by surface winds from these systems. We use synthetic databases of both historical (1980-2017) and future (2015-2050) tropical cyclone tracks to generate wind fields and force a computationally efficient wave model to estimate significant wave heights across all global tropical cyclone basins.
View Article and Find Full Text PDFArch Public Health
December 2024
Background: It is known that leprosy is a socially determined disease, but most studies using spatial analysis have not considered the vulnerabilities present in these territories.
Objectives: To measure the association between social vulnerability and the burden of leprosy in the urban space of Cuiabá.
Methods: Ecological study, carried out in Cuiabá, Brazil.
Introduction: Despite growing research, the relationship between social determinants of health (SDoH) and low back pain (LBP) remains inconsistent. This study aimed to investigate the associations between SDoH and self-reported LBP in the Portuguese population in 2019 and explore potential differences between rural and urban areas.
Methods: This is a cross-sectional study that includes 13,230 participants from the 2019 Portuguese National Health Interview Survey.