Publications by authors named "J M Alustiza Echeverria"

Introduction: Neuropathic pain is a debilitating neurological disorder and is on the rise. Since no effective treatment has been so far approved to combat the complex pathological mechanisms behind neuropathic pain, finding new therapeutic candidates is of great importance. Astaxanthin (AST) is a carotenoid with strong antioxidant, and anti-inflammatory activities.

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Background: A growing body of research is dedicated to developing new therapeutic agents for wound healing with fewer adverse effects. One of the proceedings being taken today in wound healing research is to identify promising biological materials that not only heal wounds but also vanish scarring. The effectiveness of nanofibers like polyvinyl alcohol (PVA), in improving wound healing can be related to their unique properties.

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Background: Archaeological, ethnohistorical, and ethnographic evidence supports the ubiquitous use of fermented beverages in prehispanic Chile. Made from a variety of plant raw materials, these beverages have been of special importance regarding many nutritional, medicinal, social, ritual, and religious aspects.

Purpose: The present review aims to provide a comprehensive review of the interdisciplinary information on traditional Chilean fermented beverages, as well as on the starting materials used for their elaboration.

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Article Synopsis
  • * The study systematically reviews existing research on saffron and its key components, focusing on their effectiveness against NDDs and the signaling pathways involved in their action.
  • * Results indicate that saffron and its metabolites—like crocin and safranal—can effectively manage various NDDs, including Alzheimer's and Parkinson's, by influencing apoptosis, inflammation, and oxidative stress pathways.
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Background: The genus Cass. [Asteraceae] comprises a large number of species distributed mainly in Chile and with various traditional medicinal uses.

Purpose: The present review addresses the botany, traditional uses, chemistry, biological and pharmacological activities of the genus, aiming to further potentiate the associated research and applications.

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