Evidence of spillover benefits from large-scale marine protected areas to purse seine fisheries.

Global tuna fisheries are valued at more than $40 billion, with the majority of this value derived from purse seine fisheries. Recently created large-scale marine protected areas are potentially big enough to protect highly migratory species such as tuna, possibly leading to increases in abundance (a conservation benefit) and consequent spillover near protected area boundaries (an economic benefit). Using publicly available data from nine large-scale marine protected areas across the Pacific and Indian oceans, we find that catch-per-unit-effort in tuna purse seine fisheries has increased by an average of 12 to 18% near protected area boundaries, and this increase declines with distance from the boundaries.

A global test of MPA spillover benefits to recreational fisheries.

Marine protected areas (MPAs) have been identified as one of the most effective tools to halt marine biodiversity loss. However, conflicting evidence from disparate, small-scale studies obfuscate a cohesive global picture of the role that MPAs can play in enhancing local fisheries through spillover benefits. We conducted a global analysis of trophy-size fish catches as a proxy for spillover occurring outside of fully protected MPAs, focusing on time series of recreational angling catch records.

Data on how abundance of resource inflows and punishment types affect resource extraction behavior.

The data is collected through laboratory experiments on a dynamic common pool resource game, where, in an infinitely repeated number of rounds (i.e., game ended randomly), individuals made decisions about whether to exert a high or a low effort level to extract resources.

Spillover benefits from the world's largest fully protected MPA.

Previous research has cast doubt on the potential for marine protected areas (MPAs) to provide refuge and fishery spillover benefits for migratory species as most MPAs are small relative to the geographic range of these species. We test for evidence of spillover benefits accruing from the world's largest fully protected MPA, Papahānaumokuākea Marine National Monument. Using species-specific data collected by independent fishery observers, we examine changes in catch rates for individual vessels near to and far from the MPA before and after its expansion in 2016.

The Role of Hsp90-R2TP in Macromolecular Complex Assembly and Stabilization.

Hsp90 is a ubiquitous molecular chaperone involved in many cell signaling pathways, and its interactions with specific chaperones and cochaperones determines which client proteins to fold. Hsp90 has been shown to be involved in the promotion and maintenance of proper protein complex assembly either alone or in association with other chaperones such as the R2TP chaperone complex. Hsp90-R2TP acts through several mechanisms, such as by controlling the transcription of protein complex subunits, stabilizing protein subcomplexes before their incorporation into the entire complex, and by recruiting adaptors that facilitate complex assembly.