Cardiotocography combined with ST analysis versus cardiotocography combined with fetal blood sampling in deliveries with abnormal CTG: a randomized trial.

Purpose: The aim was to investigate if intrapartum monitoring with cardiotocography (CTG) in combination with ST analysis (STAN) results in an improved perinatal outcome.

Methods: We performed a two-center randomized trial. 1013 women with term fetuses in cephalic presentation entered the trial.

Early induction of labor in high-risk intrahepatic cholestasis of pregnancy: what are the costs?

Purpose: Induction of labor among pregnant women with high levels of total bile acid (TBA) is common among clinicians. We examined, if women with intrahepatic cholestasis of pregnancy (ICP) and TBA ≥ 40 μmol/l have a higher risk of maternal-fetal complications, when labor is induced at 37 weeks of gestation, compared with induction of labor at term in women with low-risk ICP.

Methods: Retrospective cohort study of 16,185 women delivering at Roskilde University Hospital in the period 2006-2011.

Acupuncture and/or sweeping of the fetal membranes before induction of labor: a prospective, randomized, controlled trial.

Aims: To evaluate the efficacy of acupuncture, and sweeping of the fetal membranes, as methods for induction of labor.

Methods: Four hundred and seven pregnant women with normal singleton pregnancies and cephalic presentations were randomized at three delivery wards in Denmark at day 290 of gestation into groups of acupuncture, sweeping, acupuncture and sweeping and controls. The primary objective was to compare the proportion of women going into labor before induction of labor at 294 days in the four groups.

Is thrombophilia a risk factor for placenta-mediated pregnancy complications?

Purpose: To determine if thrombophilia is a risk factor for placenta-mediated pregnancy complications (PMPC) (i.e., preeclampsia, intrauterine growth restriction (IUGR), placental abruption, intrauterine fetal death and recurrent pregnancy loss).

The choice of a tocolytic for the treatment of preterm labor: a critical evaluation of nifedipine versus atosiban.

Preterm birth is the major cause of neonatal mortality and morbidity in the developed world. The perfect tocolytic that is uniformly effective with complete fetomaternal safety does not exist. Tocolytic agents differ in cost, utero-specificity, safety, efficacy and whether they are licensed for use.