Publications by authors named "J Luston"
Poly(2-oxazolines) represent promising polymer materials for biomedical applications. The activation of mouse lymphoid macrophage line P388.D1 (clone 3124) by two selected representatives of poly(2-oxazolines), namely poly(2-ethyl-2-oxazoline) (PETOX100) and poly[2-(4-aminophenyl)-2-oxazoline-co-2-ethyl-2-oxazoline] (AEOX10), was assessed in vitro.
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- Poly(2-oxazolines) with different alkyl chain lengths were evaluated for their cell cytotoxicity using the MTT assay, showing that certain monomers like 2-methyl-2-oxazoline and 2-ethyl-2-oxazoline yield non-toxic polymers.
- The study found that higher molar masses of poly(2-ethyl-2-oxazoline) (PETOX) correlate with increased cell viability, up to a molar mass of 15,000 g/mol, with aromatic and aliphatic variants demonstrating similar low cytotoxicity, making them promising for biomedical uses.
- Fluorescence techniques revealed that polymer accumulation in cells depended on concentration, while immunological tests showed that the
Synthesis and bioimmunological efficiency of poly(2-oxazolines) containing a free amino group.
J Mater Sci Mater Med
March 2010
Novel amphiphilic copolymers on the basis of 2-oxazolines containing a free amino group were prepared. The copolymers were synthesized by the living cationic polymerization of 2-ethyl-2-oxazoline (ETOX) and 2-(4-aminophenyl)-2-oxazoline (APOX). The main goal of this work was the synthesis of water soluble polymer material with the defined number of functional groups necessary for the attachment of proteins and polysaccharides.
View Article and Find Full Text PDFIn the crystal structure of the title compound, C(9)H(9)NO(3), there are strong intramolecular O-H...
View Article and Find Full Text PDFIn the crystal structure of the title compound, C(11)H(13)NO(2), there are strong intermolecular O-H...
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