Publications by authors named "J Lieber Marin"
Solid tumors vary by the immunogenic potential of the tumor microenvironment (TME) and the likelihood of response to immunotherapy. The emerging literature has identified key immune cell populations that significantly impact immune activation or suppression within the TME. This study investigated candidate T-cell populations and their differential infiltration within different tumor types as estimated from mRNA co-expression levels of the corresponding cellular markers.
View Article and Find Full Text PDFApplication of Fourier transform infrared spectroscopy (FTIR) for protozoan analysis: A systematic review.
Photodiagnosis Photodyn Ther
December 2024
Protozoa present in water for human consumption represent a significant public health risk to a greater extent in the most vulnerable populations. Identifying protozoa in a traditional way through microscopy or with more advanced technologies such as molecular biology may present limitations in sensitivity, specificity, time, and costs. Fourier Transform Infrared (FTIR) spectroscopy have potential as an alternative for the detection of protozoa in water used for human consumption.
View Article and Find Full Text PDFArticle Synopsis
- - Cholestatic liver diseases (CLD) cause damage to the liver cells and can lead to fibrosis and cirrhosis due to bile acid accumulation, with STARD1 playing a potential role in this process.
- - Research found that patients with primary biliary cholangitis had higher STARD1 levels, and mice lacking STARD1 specifically in liver cells were more resistant to liver damage and inflammation associated with bile duct blockage.
- - The study suggests that targeting STARD1 could be a promising approach for treating cholestatic liver injury, as it appears to influence bile acid levels and oxidative stress in liver cells.