Publications by authors named "J Libby"
Article Synopsis
- A study examined the effects of ten VEGF genes on Alzheimer's disease (AD) using single-nucleus transcriptome data from the prefrontal cortex of 424 participants to identify cell type-specific influences on AD endophenotypes.
- The analysis employed negative binomial mixed models, revealing associations between higher VEGF receptor expressions in specific cell types (microglia, endothelial cells, and oligodendrocytes) with increased amyloid beta load and worse cognitive performance in AD.
- Findings indicate that VEGFB may have a protective effect in neurons against Aβ accumulation, while changes in FLT1 and FLT4 are linked to poorer cognitive outcomes, underscoring the importance of cell-specific VEGF signaling in AD pathology.
Article Synopsis
- The study investigates the processes e^{+}e^{-}→D_{s}^{+}D_{s1}(2536)^{-} and e^{+}e^{-}→D_{s}^{+}D_{s2}^{*}(2573)^{-} using data from the BESIII detector, focusing on a range of center-of-mass energies.
- For the first time, the absolute branching fractions of the decay processes for D_{s1}(2536)^{-} and D_{s2}^{*}(2573)^{-} are measured, revealing values of 35.9% and 37.4% respectively.
- The research identifies a resonant structure around 4.6 Ge
We measure the complete set of angular coefficients J_{i} for exclusive B[over ¯]→D^{*}ℓν[over ¯]_{ℓ} decays (ℓ=e, μ). Our analysis uses the full 711 fb^{-1} Belle dataset with hadronic tag-side reconstruction. The results allow us to extract the form factors describing the B[over ¯]→D^{*} transition and the Cabibbo-Kobayashi-Maskawa matrix element |V_{cb}|.
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- Scientists used special data from a detector to look for rare particle decays of a type called the D_{s}^{+} decay, focusing on how it might change into other particles like kaons or pions.
- They found strong evidence for the decay D_{s}^{+}→π^{+}ϕ and also discovered a new decay D_{s}^{+}→ρ^{+}ϕ, both involving particles that decay into pairs of electrons.
- However, they didn't find strong signals for three other types of decays they were looking for, and set limits on how often those changes could happen.
Article Synopsis
- Guidelines were established at a single institution to determine which anesthesiology team is responsible for pediatric cardiac patients undergoing noncardiac surgery.
- The purpose of a survey was to evaluate how team dynamics were affected after these guidelines were put into place.
- Results showed that while practices can change quickly, achieving lasting improvements in team dynamics and workplace culture requires more time.