Publications by authors named "J Lempel"
Video-Assisted Thoracic Surgery Without Intraoperative Fluoroscopy After Microcoil Localization.
Ann Thorac Surg Short Rep
September 2023
Background: Small nodules and ground-glass opacities can present a challenge when surgeons rely on direct visualization or digital palpation. Preoperative localization improves nodule detection. We aimed to determine the efficacy and safety of video-assisted thoracoscopic surgery (VATS) nodulectomy without intraoperative fluoroscopy after computed tomography (CT)-guided microcoil localization of peripheral pulmonary nodules.
View Article and Find Full Text PDFExtrapulmonary manifestations of asthma, including fatty infiltration in tissues, may reflect systemic inflammation and influence lung function and disease severity. To determine if skeletal muscle adiposity predicts lung function trajectory in asthma. Adult SARP III (Severe Asthma Research Program III) participants with baseline computed tomography imaging and longitudinal postbronchodilator FEV% predicted (median follow-up 5 years [1,132 person-years]) were evaluated.
View Article and Find Full Text PDFArticle Synopsis
- PVDOMICS is a precision medicine initiative aimed at understanding pulmonary vascular disease (PVD) by combining clinical measurements with omic data to improve classification.
- The study involved 1,193 subjects, including different groups of pulmonary hypertension (PH), comparators with mild disease, and healthy controls; findings showed notable differences in symptoms and survival rates among the groups.
- Key results highlighted low diffusing capacity for carbon monoxide and enlarged right atrial volume in certain PH groups, frequent ground glass opacities on CT scans, and the worst transplant-free survival in group 3 PH.
Background: Relative enlargement of the pulmonary artery (PA) on chest CT imaging is associated with respiratory exacerbations in patients with COPD or cystic fibrosis. We sought to determine whether similar findings were present in patients with asthma and whether these findings were explained by differences in ventricular size.
Methods: We measured the PA and aorta diameters in 233 individuals from the Severe Asthma Research Program III cohort.
Thoracoscopic surgical resection of small peripheral pulmonary nodules can be challenging, and often preoperative localization techniques are needed to avoid conversion to open thoracotomy. In this article, we show the feasibility and benefits of performing intraoperative percutaneous microcoil localization with C-arm cone-beam CT in a hybrid operating room immediately before video-assisted thoracoscopic surgery for wedge resection of a small pulmonary nodule. This technique can provide safe and accurate localization while minimizing patient discomfort and thus enhancing the patient's experience.
View Article and Find Full Text PDF