Publications by authors named "J Leland Crane"
Article Synopsis
- Elevated lactate levels are linked to serious health issues, including sepsis and mitochondrial dysfunction, and poor lactate clearance can lead to worse outcomes in these conditions.
- Current methods for managing elevated lactate are limited, but recent findings highlight the gut's role in lactate regulation, suggesting a potential link between gut bacteria and blood lactate levels.
- This study presents a promising approach using engineered probiotic spores to deliver lactate oxidase to the gut, which successfully lowers blood lactate in mice without harming gut health or immune function.
Platypuses are a unique freshwater mammal native to eastern Australia. They are semi-aquatic, predominantly nocturnal, and nest in burrows dug into the banks of waterbodies. Quantifying nesting burrow characteristics is challenging due to the species' cryptic nature.
View Article and Find Full Text PDFA woman in her 70s presented with features of hyperandrogenism including clitoral enlargement and deepening of her voice. Biochemical investigations revealed raised plasma androgens and urinary androgen metabolites and imaging findings showed a highly F-18 fluorodeoxyglucose (FDG)-PET avid left adrenal tumour initially suspected to be a malignant adrenocortical carcinoma (ACC). She subsequently underwent an uncomplicated laparoscopic adrenalectomy where complete resection of her tumour was achieved.
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