Publications by authors named "J Ledingham"
Objectives: People with inflammatory arthritis (IA) experience worsened mental wellbeing alongside disease progression. Using the National Early Inflammatory Arthritis Audit (NEIAA), we assessed trends in psychological distress during 12-months following IA diagnosis, mapping these against clinical outcomes to identify associations.
Methods: This is a prospective study of people recruited to NEIAA receiving an IA diagnosis and completing the baseline patient survey.
Background: Gout is the most prevalent inflammatory arthritis, yet one of the worst managed. Our objective was to assess how the COVID-19 pandemic impacted incidence and quality of care for people with gout in England, UK.
Methods: With the approval of National Health Service England, we did a population-level cohort study using primary care and hospital electronic health record data for 17·9 million adults registered with general practices using TPP health record software, via the OpenSAFELY platform.
Objectives: Inflammatory arthritis causes significant work disability. Studies regarding this frequently fail to report important contextual information such as employment type. Our objective was to explore work participation, by gender and occupation type, in early inflammatory arthritis.
View Article and Find Full Text PDFObjective: Online patient-reported outcome measures (PROMs) enable remote collection of perceptions of health status, function, and well-being. We aimed to explore patterns of PROM completion in patients with early inflammatory arthritis (EIA) recruited to the National Early Inflammatory Arthritis Audit (NEIAA).
Methods: NEIAA is an observational cohort study design; we included adults from this cohort with a new diagnosis of EIA from May 2018 to March 2020.
Article Synopsis
- The study aimed to identify risks and predictors of hospitalization and mortality due to COVID-19 in patients with early inflammatory arthritis (EIA) recruited to the National Early Inflammatory Arthritis Audit (NEIAA).
- Out of 14,127 patients with EIA, there were 143 COVID-19 hospitalizations and 47 deaths, with certain factors like age, gender, comorbidities, and previous smoking increasing the risk.
- The findings suggest that patient characteristics have a more significant impact on COVID-19 outcomes than the initial treatment strategy, but the study did not account for changes in treatment over time.