Colonic histiocytic neoplasm mimicking malignant histiocytosis and presenting as intussusception.

It is now apparent that distinction between the so-called malignant histiocytosis and lymphoma can be made using panels of established immunohistochemical markers and/or genotypic analysis. Many, if not all, of the previously diagnosed cases of malignant histiocytosis have been shown to be of lymphoid, rather than histiocytic, lineage. We report a rare case of colonic histiocytic neoplasm accompanied by a lymphoreticular dissemination that mimicked that of malignant histiocytosis.

Mechanisms of protein activation of the intestinal phase of gastric secretion.

To determine if the secretory response to protein in the gut is due to direct effects of absorbed amino acids on the parietal cells, to hormonal effects, or to a combination of both, Heidenhain pouch secretion and plasma amino nitrogen levels were measured during enteral infusions of casein or liver extract, as well as during intravenous infusions of amino acids, in three dogs with and three dogs without portacaval transposition. In the dogs without portacaval transposition, gastric secretory responses were slight and did not differ significantly; secretory responses were seen only during infusions in which elevations of plasma amino nitrogen values occurred. In dogs with portacaval transposition, secretory responses to both casein and liver extract were significantly higher (P less than 0.

Control of the Zollinger-Ellison syndrome by excision of primary and metastatic tumor.

In a patient with Zollinger-Ellison syndrome, control of the peptic ulcer diathesis was attempted by excision of a small duodenal gastrinoma and removal of three lymph nodes containing metastases. The patient has been asymptomatic for 2.5 years with basal achlorhydria, a normal serum gastrin level and a negative gastrin response to secretin.