Publications by authors named "J Lammens"
Continuous spin-freeze-drying is an innovative pharmaceutical manufacturing approach offering real-time monitoring and control at the individual vial level, unlike conventional batch lyophilization. A central feature of this technology is spin-freezing, which involves rapidly spinning liquid-filled vials under a precisely controlled cold gas flow, resulting in a thin, uniform frozen product layer. Using a model peptide formulation, we investigated the impact of different cooling and crystallization rates on quality attributes (QA) and primary drying duration.
View Article and Find Full Text PDFThe Ilizarov technique is a well-known procedure for limb deformity corrections. However, in the present study, the purpose was to examine the potential of wound closure by means of an Ilizarov frame. Two main cases are presented, a further seven were retrospectively reviewed.
View Article and Find Full Text PDFArticle Synopsis
- Hallux valgus surgery can sometimes make the first metatarsal bone shorter, which leads to foot pain and unhappy patients.
- To fix this problem, doctors used a method called distraction osteogenesis to lengthen the first metatarsal bone in three patients using a special frame.
- The results showed that the surgery improved the foot's shape, relieved pain, and the method is considered affordable and effective, but doctors need to watch closely to avoid making the bone too long.
The original Papineau technique described satisfactory results in treating infection-related pseudarthrosis and chronic osteomyelitis with chronic draining wounds. We described our experience in treating these soft tissue defects using the Papineau-irrigation technique. We retrospectively reviewed the records of patients that were treated with the Papineau-irrigation technique at UZ Leuven, Belgium, between January 2006 and January 2023.
View Article and Find Full Text PDFBackground: Coronary computed tomography angiography (CCTA) -derived fractional flow reserve (FFR) is recommended to evaluate the functional consequences of obstructive coronary artery disease (OCAD). Real-world incremental impacts of FFR use still remains under debate.
Methods: 1601 patients with suspected OCAD on CCTA (>50 % stenosis), including 808 (50.