Publications by authors named "J Lakshimi A"
Mandibular premolars exhibit intricate and diverse root canal anatomy, presenting substantial challenges in endodontic treatment. Uncommon variations, such as the presence of three canals, demand meticulous diagnostic and therapeutic approaches to mitigate the risk of overlooking canals and subsequent treatment failure. This case report highlights three cases of mandibular premolars exhibiting a rare root canal configuration with one mesial and two distal canals, successfully managed using cone beam computed tomography (CBCT) for accurate diagnosis and ultrasonic activation for disinfection.
View Article and Find Full Text PDFSafety is crucial in the railway industry because railways transport millions of passengers and employees daily, making it paramount to prevent injuries and fatalities. In order to guarantee passenger safety, computer vision, unmanned aerial vehicles (UAV), and artificial intelligence will be essential tools in the near future for routinely evaluating the railway environment. An unmanned aerial vehicle captured dataset for railroad segmentation and obstacle detection (UAV-RSOD) comprises high-resolution images captured by UAVs over various obstacles within railroad scenes, enabling automatic railroad extraction and obstacle detection.
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- Hepatic alveolar echinococcosis is a zoonotic disease prevalent in western China, especially in regions like Qinghai, Tibet, and Xinjiang.
- Research shows that neovascularization in this disease is linked to the overexpression of VEGFA and HIF-1α, which play key roles in angiogenesis.
- The article explores the potential for treating hepatic alveolar echinococcosis by targeting signaling pathways similar to those used in liver cancer therapies, focusing on the biological roles of HIF-1α, VEGFA, and the BMP9-ID1 signaling pathway.
Article Synopsis
- * Current treatment primarily involves surgery or lifelong use of anti-AE medications like albendazole and mebendazole, which can manage the disease but are not curative and may cause harmful side effects.
- * New potential therapies are being explored, including synthetic and natural compounds, which aim to improve effectiveness and reduce side effects by targeting the parasitic metabolism and structure, with ongoing research to refine these treatment options.
Background: Neck extensor muscles frequently exhibit poor performance in individuals with neck pain. The Deep Neck Extensor Endurance Test (NEET) is commonly used to assess the isometric holding time of the neck extensor muscles. Establishing normative values for this test may assist clinicians in the development of rehabilitation programs.
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