Publications by authors named "J Lacasse"

Article Synopsis
  • Hormonal contraceptives (HCs) are widely prescribed for various purposes, yet their effects on the brain are not thoroughly understood, necessitating more research.
  • Recent studies, including human neuroimaging and nonhuman animal research, highlight potential links between HCs and mood disorders, especially regarding changes in the hypothalamic-pituitary-adrenal (HPA) axis.
  • The review points out that adolescents may be particularly sensitive to HCs and stresses the importance of individualized research due to variability in HC formulations and user factors for better women's health outcomes.
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During maze navigation rats can rely on hippocampus-mediated place memory or striatum-mediated response memory. Ovarian hormones bias whether females use place or response memory to reach a reward. Here, we investigated the impact of the contraceptive hormones, ethinyl estradiol (EE) and levonorgestrel (LNG), on memory bias.

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Research on hormonal contraceptives (HC) in animal models is lacking, and as a result, so is our understanding of the impact of HC on the brain and behavior. Here, we provide a review of the pharmacology of HC, as well as the methodology and best practices for designing a model of HC in female rats. We outline specific methodological considerations regarding dosing, route of administration, exposure time/timing, and selecting a control group.

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Technology can expand access to specialty health services for disadvantaged and underserved populations. A novel psychiatric consultation service involving both electronic consultations (e-consultations) and telephonic consultations (tele-consultations) was implemented by hospital-based staff and trainee psychiatrists in 12 primary care sites within a public safety-net health system. Utilization data were collected over a three-year period.

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