Publications by authors named "J LANDAU"
Background: The identification and drug targeting of cancer causing (driver) genetic alterations has seen immense improvement in recent years, with many new targeted therapies developed. However, identifying, prioritizing, and treating genetic alterations is insufficient for most cancer patients. Current clinical practices rely mainly on DNA level mutational analyses, which in many cases fail to identify treatable driver events.
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- The PATH program at University Medical Center aims to address chronic pain, which affects about 20.9% of the US population, through an integrative approach within a bundled payment model.
- The program saw high participation rates, with 88.8% of enrollees completing it and reporting significant improvements in pain interference, enjoyment of life, and overall mental health metrics after the program.
- Financially, the program led to an 18% reduction in total care costs and a significant decrease in emergency room visits for both general and pain-related issues.
Article Synopsis
- A 4.2-cm hepatic artery aneurysm developed in a patient after they underwent pancreaticoduodenectomy surgery, affecting the right hepatic artery.
- Due to a lack of collateral blood flow and difficulties in placing a covered stent, treatment involved using a saphenous vein graft to bypass the affected artery.
- A follow-up CT scan after one year showed that the bypass was successful, highlighting the importance of preserving arterial flow and exercising caution in performing hepatic embolization in such cases.
Aim: The objectives of this study were to assess the return of spontaneous circulation rates and hemodynamic response of large swine (>65Kg) during cardiopulmonary resuscitation after nontraumatic cardiac arrest using the COBRA-OS® aortic occlusion balloon and to address limitations of large swine closed-chest cardiopulmonary resuscitation by comparing closed-chest vs. open-chest cardiopulmonary resuscitation.
Methods: Yorkshire pigs ( = 10) weighing >65 kg were anesthetized and ventilated.