Publications by authors named "J L Vandeberg"

Article Synopsis
  • Surgical care in the operating room creates a lot of greenhouse gas emissions, making up a third of healthcare's total emissions.
  • A big study looked at many articles about how gastrointestinal surgery affects the environment to find ways to make it more sustainable.
  • The results showed that using less anesthetic gases and reducing surgical waste can significantly help lessen the impact on the environment, and having special teams to promote these changes is a good idea.
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Article Synopsis
  • Surgeons around the world are interested in making surgery more eco-friendly, so a group was formed to learn more about their thoughts on this topic.
  • They sent out a survey to understand how surgeons feel about being sustainable, how much they know about the carbon footprint of their surgeries, and what changes they are willing to make.
  • The results showed that most surgeons want to help the environment but don’t know much about how their practices affect it; they prefer learning through online resources.
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  • This study investigates the brain development of the marsupial Monodelphis domestica, highlighting its unique postnatal growth due to being born immature without placental support.
  • Researchers used RNA-sequencing to analyze the expression of transporters and enzymes in the brains of newborn to juvenile Monodelphis, comparing the findings with data from developing eutherian rats.
  • Results showed that Monodelphis has early limitations in drug entry into the brain, but compensates for the lack of placental protection by activating protective mechanisms during brain development.
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Article Synopsis
  • The healthcare system has a big impact on the environment, especially operating rooms, which contribute a lot to carbon emissions.
  • Major organizations and governments are working together to make healthcare more sustainable and reduce its carbon footprint.
  • A new group called the Sustainability in Surgical Practice task force was formed to promote better practices and encourage actions that help both surgery and the environment.
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Steady-state expression quantitative trait loci (eQTLs) explain only a fraction of disease-associated loci identified through genome-wide association studies (GWASs), while eQTLs involved in gene-by-environment (GxE) interactions have rarely been characterized in humans due to experimental challenges. Using a baboon model, we found hundreds of eQTLs that emerge in adipose, liver, and muscle after prolonged exposure to high dietary fat and cholesterol. Diet-responsive eQTLs exhibit genomic localization and genic features that are distinct from steady-state eQTLs.

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