Publications by authors named "J L Vachiery"
Background: RV reserve has been linked to exercise capacity and prognosis in cardiopulmonary diseases. However, evidence in this setting is limited, due to the complex shape and load dependency of the RV. We sought to study right ventricular (RV) adaptation to exercise by simultaneous three-dimensional echocardiography (3DE) and right heart catheterization (RHC).
View Article and Find Full Text PDFBackground: Invasive exercise right heart catheterization is a gold standard in diagnosing heart failure with preserved ejection fraction (HFpEF). Body positions during the test influence hemodynamics. However, the discrepancy in HFpEF diagnosis between exercise testing in supine versus upright position is unknown.
View Article and Find Full Text PDFArticle Synopsis
- Pulmonary arterial hypertension (PAH) is a serious, rare illness that affects blood vessels in the lungs and can lead to heart failure and even death.
- Current treatments work on three main areas but don't cure the disease, so researchers are looking for new options.
- Sotatercept is a new medication that helps improve patients' health and quality of life, and it's been shown to be safe, though it can cause some side effects.
Article Synopsis
- Left heart disease (LHD) is a leading cause of pulmonary hypertension (PH), further classified into isolated post-capillary (ipcPH) or combined pre- and post-capillary PH (cpcPH).
- Recent clinical trials emphasize avoiding pulmonary arterial hypertension treatments for PH-LHD patients outside of trials, as these treatments may cause harm.
- A new PH-LHD staging system categorizes patients into four stages based on their clinical and hemodynamic characteristics, which aims to improve diagnosis and treatment through a more individualized approach.