Publications by authors named "J L Trillo"
Article Synopsis
- Chronic kidney disease (CKD) poses significant challenges for healthcare systems due to its high morbidity and resource demands, prompting a need for an optimal care model through a multidisciplinary approach.
- A panel of 59 CKD experts identified 38 key factors for improving patient care, focusing on enhancing CKD visibility, prevention, early diagnosis, coordinated monitoring, and training for both healthcare providers and patients.
- The study emphasizes a collective agreement on prioritizing CKD care by fostering prevention, early detection, and comprehensive monitoring to improve outcomes at institutional and societal levels.
Healthcare workers are subjected to numerous work-related stress factors, which have negative consequences on their physical and mental health, making them a vulnerable group. The recent pandemic caused by the new coronavirus created a high demand for attention from healthcare workers, which put their mental health at risk. This study aimed to test a mediation model in which resilience and the satisfaction of psychological needs play a mediating role in risk perception, the attitude toward the management carried out by the administration, emotional intelligence on psychological wellbeing, and depressive symptoms of frontline professionals.
View Article and Find Full Text PDFIntroduction: The value of gene therapies for haemophilia needs to be assessed holistically.
Aim: To determine the value of etranacogene dezaparvovec (ED) compared to current extended half-life (EHL) recombinant factors (rFIX), using multi-criteria decision analysis (MCDA).
Method: MCDA EVIDEM methodology adapted to orphan drugs was used, with nine quantitative criteria and four contextual criteria.
There are mixed findings on the association of hypertension or gastrointestinal bleed (GIB) with mortality in COVID-19 patients but no research on the combination of both hypertension and GIB with mortality in COVID-19 patients. We study in COVID-19 patients the association of hypertension and GIB with mortality, acute kidney injury (AKI), vasopressor use, and/or mechanical ventilation. This is a retrospective study of COVID-19 patients who were categorized into groups of no GIB/no hypertension (n = 653), yes hypertension/no GIB (n = 1,620), yes GIB/no hypertension (n = 104), or yes GIB/yes hypertension (n = 334).
View Article and Find Full Text PDFObjectives: The aim of this study was to review the current evaluation and funding processes for new drugs in different developed countries, to provide a comparative framework with detailed, homogeneous, and up-to-date information.
Methods: Scientific publications, reports and websites were reviewed between July and December 2021 using PubMed, Google Scholar, and grey literature sources. The main items searched were actors and processes, including timelines, characteristics of clinical and economic evaluations, participation of stakeholders, elements of price and reimbursement decisions, cost-effectiveness thresholds and specific funds.