Cancer incidence and exposure to 4,4'-methylene-bis-ortho-chloroaniline (MbOCA).

Aims: To monitor the occurrence of cancer in a recently defined cohort of UK workers engaged in the manufacture of polyurethane elastomers using 4,4'-methylene-bis-ortho-chloroaniline.

Methods: A cohort of 308 male production workers from seven factories have been enumerated. All employees had a minimum of 12 months employment and were first employed at one of the participating factories in the period 1973-2000.