Publications by authors named "J L Schmit"
Article Synopsis
- * The study focused on JEN-101, a localized injection of interleukin-12 designed to boost immune response in dogs with advanced melanoma, evaluating its safety, effectiveness, and immune effects over several doses.
- * Results indicated that JEN-101 was well-tolerated with manageable side effects, and it showed promising biological responses, suggesting its potential for further research and relevance to human cancer treatment.
Article Synopsis
- Compartment syndrome in the upper extremity is a critical condition typically resulting from specific injuries like fractures or burns.
- An unusual case involved an older woman who developed acute nontraumatic compartment syndrome due to acquired factor VIII deficiency, requiring a team of various medical specialists for diagnosis and treatment.
- Elevated partial thromboplastin time in a bleeding patient should indicate potential factor VIII deficiency, necessitating prompt evaluation and a coordinated treatment approach for better recovery.
Article Synopsis
- This study analyzes how phase-separated compartments can influence enzymatic reactions, highlighting both the benefits of increased reactant concentration and the drawbacks of reduced mobility.
- While phase separation can enhance reactions under certain conditions, it can also hinder them if reactants become too immobilized, particularly in high-order or sequential reactions.
- An optimal balance of sticker affinity and spatial arrangement in the dense phase can maintain reactant mobility, suggesting that phase separation has significant potential to function as a reaction facilitator in cellular environments.
Zinc, a vital trace element, holds significant importance in numerous physiological processes within the body. It participates in over 300 enzymatic reactions, metabolic functions, regulation of gene expression, apoptosis and immune modulation, thereby demonstrating its essential role in maintaining overall health and well-being. While zinc deficiency is associated with significant health risks, an excess of this trace element can also lead to harmful effects.
View Article and Find Full Text PDFThe interaction of liquid water with hydrophobic surfaces is ubiquitous in life and technology. Yet, the molecular structure of interfacial liquid water on these surfaces is not known. By using a 3D atomic force microscope, we characterize with angstrom resolution the structure of interfacial liquid water on hydrophobic and hydrophilic silica surfaces.
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