Publications by authors named "J L Sanchez-Iglesias"

Article Synopsis
  • Researchers looked at two blood tests, procalcitonin and CRP, to see if they could help predict problems after surgery for advanced ovarian cancer.
  • They studied 92 patients and found that higher levels of these markers were linked to a condition called anastomotic leakage, where the surgical connections in the bowel may fail.
  • The best time to check these blood tests for accurate results was found to be day 1 for procalcitonin and day 3 for CRP after surgery.
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Background: High-grade serous carcinoma (HGSC) is the most common and deadly subtype of ovarian cancer. Although most patients will initially respond to first-line treatment with a combination of surgery and platinum-based chemotherapy, up to a quarter will be resistant to treatment. We aimed to identify a new strategy to improve HGSC patient management at the time of cancer diagnosis (HGSC-1LTR).

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Objective: To investigate the impact of discontinuation of mechanical bowel preparation in advanced ovarian cancer surgery within the context of the ERAS program.

Methods: We retrospectively reviewed the medical records of patients with advanced ovarian cancer who underwent cytoreductive surgery with simultaneous colon and/or rectal resection from January 2012 to November 2020. Patients were divided into two groups based on whether preoperative mechanical bowel preparation (MBP) was given (pre-ERAS) or not (post-ERAS).

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