Publications by authors named "J L Poblete"
The global dried blueberry market is steadily growing, driven by the creation of innovative blueberry-based products. This trend presents an opportunity to explore a previously untapped segment of the blueberry market in Chile. In this study, a comprehensive assessment of four drying techniques (hot-air drying [HAD], vacuum drying [VD], infrared drying [IRD], and freeze-drying [FD]) was conducted to determine best operating conditions and preserve the health-promoting properties of blueberries.
View Article and Find Full Text PDFThe search and identification of inhibitory molecules from novel natural sources, such as pisco grape pomace extract obtained by green techniques, may help to develop agents with therapeutic potential that are beneficial to health with fewer adverse effects than drugs. Many drugs act as enzyme inhibitors, decreasing their activity and thus correcting a metabolic imbalance. This study aims to identify bioactive molecules with antioxidant and inhibitory activity over acetylcholinesterase and cyclooxygenase enzymes present in pisco grape pomace green extracts.
View Article and Find Full Text PDFArticle Synopsis
- Acute kidney injury (AKI) is a serious complication in critically ill patients, and early detection through biomarkers like TIMP-2 and IGFBP-7 can improve treatment outcomes.
- * A study involving 135 ICU patients found that urine levels of TIMP-2/IGFBP-7 could effectively predict both AKI and major adverse kidney events within 30 days, using a threshold of 0.3 ng/mL.
- * The results showed a high sensitivity and specificity for detecting AKI, indicating its potential as a valuable diagnostic tool in high-risk populations.
Objectives: This preliminary study determined the prevalence of HIV infection among patients with newly diagnosed solid and hematologic malignancies at the Philippine General Hospital - Cancer Institute.
Methods: Adult Filipinos aged 19 years and above with biopsy- or imaging-confirmed malignancy and for chemotherapy, seen at the adult medical oncology and hematology clinic from January to September 2021 were included. Demographic and clinical data were obtained using a questionnaire.
Aim: To provide a comprehensive and more representative national data on the disease, especially on treatment options and outcomes, and to determine access of retinoblastoma patients from Luzon, Visayas and Mindanao to eye care, and determine if access is associated with delay in consultation, staging and outcomes.
Methods: Cohort study of retinoblastoma patients seen in eleven institutions located in the three major areas of the Philippines namely Luzon, Vizayas and Mindanao from 2010-2020.
Results: Totally 636 patients, involving 821 eyes, were included.