Publications by authors named "J L Perret"

Background: Life-course lung function trajectories leading to airflow obstruction, as measured by impaired FEV/FVC (forced vital capacity), precede the onset of chronic obstructive pulmonary disease (COPD). We aimed to investigate whether individuals on impaired FEV/FVC trajectories have an increased burden of respiratory symptoms, including those who do not meet the spirometric criteria for COPD.

Methods: We analysed serial life-course data from two population-based cohort studies separately, which included respiratory symptoms and spirometry: the Tasmanian Longitudinal Health Study (TAHS, Australia) cohort was recruited at age 6-7 years and followed up until middle age (mean age 53 years; range 51-55); and the Coronary Artery Risk Development in Young Adults (CARDIA, USA) cohort was recruited at a mean age of 25 years (range 18-30) and followed up to a mean age of 55 years (range 47-64).

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Article Synopsis
  • - The study analyzed smoking trends in Australia from 1910 to 2005, focusing on initiation and cessation rates among different age groups and genders to assess the impact of historical tobacco control policies.
  • - Among nearly 30,000 participants, 56.8% reported having smoked, with young males showing consistently high initiation rates from 1910-1999, while young females saw a significant rise in smoking in the 1960s and 1970s.
  • - The results revealed that while smoking cessation rates increased overall for ages 36-50, they plateaued for females and decreased for males post-1990, highlighting the varying effectiveness of tobacco control measures, particularly among younger individuals.
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Background: Studies exploring early life-course BMI trajectories and subsequent mental health outcomes are limited but may provide important insights for early intervention. We investigated associations between BMI trajectories from 0 to 18 years and mental health outcomes in emerging adulthood.

Methods: Data were obtained from 434 participants in the Melbourne Atopy Cohort Study (MACS).

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Introduction: Evidence on the early life risk factors of adult CRS, and the history of asthma and allergies across the life course, is limited.

Aim: To investigate relationships between respiratory infective/allergic conditions in childhood, and asthma and allergies across the life course and CRS in middle age.

Methods: Data were from the population-based Tasmanian Longitudinal Health Study (TAHS) cohort, first studied in 1968 when aged 6-7 years (n = 8583) and serially followed into middle age (n = 3609).

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